Isagenix e Natural Balanced Energy Shot Adaptogens Apple Pomegranate 12 pack

Energy & Focus

e+ Energy Shot — 12ct

The twelve-pack of the adaptogen energy shot.

12 shots · $5.00 per shot

$60 US retail

As an Isagenix Brand Partner we earn from qualifying purchases made through this link. Prices are US retail, sourced April 2026. Full disclosure.

Carton

12 shots

Ages 16+

Why Isagenix makes this one

What it was built to do

Portable, dose-adjustable clean caffeine; the original adaptogens-plus-caffeine expression.

What actually makes it different

85mg from green tea and yerba maté, the only yerba maté product in the line; splittable dose.

Who it suits

Ages 16+, Cleanse Day approved.

The dividing line

BEA Sparkling: the brand says BEA is about 1.5 servings of e+. Dose and carbonation only.

Details the shop page leaves out

  • 85mg of naturally sourced caffeine split across green tea leaf and yerba maté, with Siberian ginseng, hawthorn berry and schisandra. Its cited study specifically targeted highly stressed and fatigued people.

At a glance

CategoryEnergy & Focus
FormatCarton
Size12 shots
Retail price$60
Cost per shot$5.00
Suggested minimum age16 and over (Isagenix guidance)

Flavors and variants

  • Apple Pomegranate

The research on this product, and who paid for it

e+ Energy Shot — 12ct is one of the few items in the line with a published trial naming it specifically. Here is what exists, in full, including the parts that do not flatter it.

Caffeine-containing, adaptogenic-rich drink modulates the effects of caffeine on mental performance and cognitive parameters

Published inNutrients, 2020
ReferencePMID 32610481
DesignPlacebo-controlled, double-blinded, randomised crossover; 30 participants
What was testedThis product
Who funded itFunded by Isagenix; one author was an Isagenix employee and the investigators received funding to conduct the work

The comparison was against both a placebo and caffeine alone, and the outcomes were mixed rather than uniformly favourable. ‘Better than caffeine’ is not what this study found, and it is not what this page says.

A company-funded study is not worthless and it is not proof. It is one result, produced by people with an interest in the outcome, and it is worth exactly as much as its design allows. That is why the funding sits next to the finding here rather than in a footnote.

What the evidence actually shows

Company-funded product trial — cognition and mood

A placebo-controlled, double-blind randomised crossover in 30 people comparing the e+ shot against a matched caffeine shot and a placebo. Both caffeinated drinks affected some cognitive and mood measures, but many comparisons between e+ and plain caffeine were not significantly different. Systolic blood pressure rose at 30 minutes for both, staying within healthy ranges. Isagenix-funded with a company-affiliated author. It does not show that the adaptogens outperform caffeine on their own.

Allergens can differ between flavors, so check the pack you receive. Full allergen and manufacturing statement.


Where to buy it

This goes straight to the product on our storefront.

The full catalogue with current retail pricing lives on the shop page.

How this compares in Energy & Focus

11 products sit in Energy & Focus. Here they are on the four numbers that separate them.

ProductSizeRetailPer serving
e+ Energy Shot — 12ct12 shots$60$5.00
e+ Energy Shot — 6ct6 shots$32$5.33
BEA Sparkling Energy12 cans$61$5.08
BEA Glow — 6ct6 cans$47$7.83
BEA Glow — 30ct30 cans$228$7.60
XM+ Energy Mix30 packets$149$4.97
Nootropic Elixir — 10ct10 bottles$61$6.10
Nootropic Elixir — 40ct40 bottles$232$5.80
Nootropic Elixir — 60ct60 bottles$311$5.18