Tri-Release Protein — 1ct
Whey, egg white and milk protein staged for slower release.
28 servings · $2.14 per serving
$60 US retail
As an Isagenix Brand Partner we earn from qualifying purchases made through this link. Prices are US retail, sourced April 2026. Full disclosure.
Canister
28 servings
Ages 18+
2 flavors
In 3 packs
Why Isagenix makes this one
What it was built to do
Extend the duration of muscle protein synthesis rather than the size of the dose.
What actually makes it different
25g staggered whey isolate, egg white and milk protein, plus patented Velositol.
Who it suits
Ages 18+, pre-, intra- or post-workout or between meals, up to four servings.
The dividing line
IsaPro: release profile and Velositol. Performance Protein: supplement versus complete meal.
What the system-level research shows
Several published trials involve these products, funded by unrestricted Isagenix grants with company employees or advisers among the authors. They test a whole protocol — protein pacing with calorie restriction or intermittent fasting — not a single shake. In one head-to-head over eight weeks the protein-pacing group lost more weight and more visceral fat than a heart-healthy comparison diet, and reported lower desire to eat. In a 52-week follow-up the control group trended back toward baseline on most markers despite a lower average calorie intake. Those are findings about a programme. They are not evidence that this one product, bought on its own, produces that result, and this site will not present them that way.
The trials, named. Intermittent fasting combined with calorie restriction is effective for weight loss and cardio-protection in obese women (Nutrition Journal, 2012, PMID 23171320); Improvement in coronary heart disease risk factors during an intermittent fasting/calorie restriction regimen: relationship to adipokine modulations (Nutrition & Metabolism, 2012, PMID 23113919); Protein-pacing caloric-restriction enhances body composition similarly in obese men and women during weight loss and sustains efficacy during long-term weight maintenance (Nutrients, 2016, PMID 27483317); Intermittent fasting and protein pacing are superior to caloric restriction for weight and visceral fat loss (Obesity, 2023, DOI 10.1002/oby.23660, trial NCT04327141); Gut microbiome remodeling and metabolomic profile improves in response to protein pacing with intermittent fasting versus continuous caloric restriction (Nature Communications, 2024, follow-up analysis of the 2023 trial above). The first two are the same cohort of 54 women reported twice, so that is four independent studies rather than five, and every one of them was paid for by Isagenix.
At a glance
| Category | Shakes |
| Format | Canister |
| Size | 28 servings |
| Retail price | $60 |
| Cost per serving | $2.14 |
| Suggested minimum age | 18 and over (Isagenix guidance) |
Flavors and variants
- Chocolate Milk
- Vanilla Custard
The label, on file with the federal government
The US National Institutes of Health keeps a public database of dietary supplement labels. AMPED Tri-Release Protein, Vanilla Custard is in it. This is what the panel said when it was recorded on 26 December 2020 — serving size 37.5 g (1 scoop), 28 servings to the container.
| Per serving | Amount | % Daily Value |
|---|---|---|
| Calories | 140 | — |
| Total fat | 1.5 g | 2% |
| Saturated fat | 1 g | 5% |
| Cholesterol | 10 mg | 3% |
| Total carbohydrate | 6 g | 2% |
| Total sugars | 2 g | — |
| Added sugars | 1 g | 2% |
| Protein | 25 g | 50% |
| Calcium | 310 mg | 24% |
| Phosphorus | 170 mg | 14% |
| Chromium | 500 mcg | 1,429% |
| Sodium | 150 mg | 7% |
| Potassium | 110 mg | 2% |
| Muscle-building matrix | 31.75 g | — |
Muscle-building matrix: 31.75 g. Declared as a single figure covering 4 ingredients — Undenatured whey protein isolate, Undenatured milk protein concentrate, Egg white protein, Velositol amylopectin chromium complex. A proprietary blend is legal and common, but it means the label does not tell you how much of any one of them you are getting.
Other ingredients. Medium-chain triglyceride oil powder, fructose, digestion-resistant maltodextrin, natural flavors, xanthan gum, sea salt, stevia leaf extract.
The three protein sources are the release profile the name refers to: whey isolate fast, milk protein concentrate slower, egg white in between. 500 mcg of chromium is 1,429% of the daily value and comes from the Velositol complex, not added separately.
Source: NIH Dietary Supplement Label Database, record 238829, captured 26 December 2020. DSLD is authoritative for what a label said on the date it was recorded. It is not evidence that a product works or is safe, inclusion is not an endorsement, and the formula may have changed since. Check the pack you receive.
Is that a lot? What the rest of the shelf looks like
Meal-replacement shakes in this tier commonly run 16 to 25 g of protein and 130 to 240 calories a serving, with around 6 g of fibre, and land between roughly $3.20 and $4.35 a serving at full price. The spread inside that range is mostly a positioning choice: the lower-calorie end is built as a protein supplement you add to a day, the higher end as a meal you replace. Compare protein per calorie and protein per dollar separately from micronutrient completeness — a powder that wins on cost per gram of protein is not answering the same question as one built to stand in for a meal.
Category figures checked August 2026 across mainstream products in the same format, from the manufacturers’ own published labels and pricing. We do not name other brands on this site — a brand name does not tell you whether a dose is high or low, and a range does.
Allergens can differ between flavors, so check the pack you receive. Full allergen and manufacturing statement.
Packs that include this
Tri-Release Protein — 1ct appears in 3 of the 53 packs Isagenix sells. If you are buying it alongside other products, one of these is usually the cheaper route.
| Pack | Covers | Retail | Per covered day |
|---|---|---|---|
| Lean Muscle Essentials Pack | 30 days | $331 | $11.03 |
| Bedtime Belly Buster Bundle | 30 days | $139 | $4.63 |
| AMPED Core Bundle | — | $160 | — |
Where to buy it
This goes straight to the product on our storefront.
If you would rather compare before deciding, the shop page lists all 134 items with cost per serving.
How this compares in Shakes
7 products sit in Shakes. Here they are on the four numbers that separate them.
| Product | Size | Retail | Per serving |
|---|---|---|---|
| Tri-Release Protein — 1ct | 28 servings | $60 | $2.14 |
| IsaLean Protein Shake | 14 meals | $73 | $5.21 |
| IsaLean Protein Shake, Plant-Based | 14 meals | $75 | $5.36 |
| IsaLean Performance Protein | 14 meals | $84 | $6.00 |
| Tri-Release Protein — 2ct | 56 servings | $120 | $2.14 |
| IsaPro Whey Protein | 30 servings | $65 | $2.17 |
| Clear Protein | 10 servings | $53 | $5.30 |